Nathan Stone returns to his Virginia home to discover that the horrors of the Civil War are not over; his family has been wiped out, and their home burned by seven renegades. Nathan swears an oath on his father's grave to find and kill each of the men responsible. He begins a lonely journey that will take him south and west, on a vengeance trail that crosses the paths of some infamous figures, including "Wild Bill" Hickok, Roy Bean, and Frank & Jesse James. Along the way, Nathan Stone becomes one of the greatest gunslingers of the time, handing out bloody justice to the men who took his family.