Nemsis, a former Disciple of the LabCreator, rises and sides with the Horde led by Sharinia. Deandrea and T'orkh come to Nemsis's aid when her life is threatened by the Devil of Death and the Kroo, a powerful tribe of cloned modified humans.
In Oval-Citá, the Holy City, Tmara and her friends search for the Golden Spirit. However, they find Inanna the High Priestess on their way, who joins the Pact of Madness with an army of cyborgs.
Neptus, king of Oval-Lantis, and some of his subjects seek help from the Pirates of Carnishar in their battle against the Bringer of Doom, which ends less well.
The Horde is threatened by the Talpidaes and makes a pact with the Zulus. Together they set out for the mighty Maistro City, which is threatened by The Pact of Madness.
Will the Pact of Madness take over from the LabCreator? Or does the story end in a confrontation between the LabCreator and Nemsis? And which side do the Oval-Lathans and the other peoples take in the struggle between the insane and the learned, or is there no distinction to be made between them? What role do the Masters of Hollow Earth play?

And the LabCreator awakens, ready for his Blessing planned for over a millennium; the apocalypse for humanity is here...