All fifteen-year-old Noah Hipwell wants is to go through high school in peace. Yet he finds himself suspended after a bully pushes him too far, and Noah's forced to defend himself. His mother, fed up with the school's indifference to his plight, pulls him out completely and leaves Noah uncertain of his future while they look for a good and safe school for him.
All Dorothy "Dot" Hipwell wants is to go through single motherhood in peace. Yet she and her son are harassed by weekly phone calls from her evangelical family hell-bent on guilt-tripping them both back into the fold. Then Noah's grandparents ask strange questions about their old van after dropping cryptic references to a group called The Soul Warriors. Fed up, Dot takes Noah away for a much-needed getaway, only to find themselves suddenly transported to an alternate world, where a town called Helleville awaits them and all other condemned souls.
Along with warm-blooded, living human beings, the Hipwells rub shoulders with zombies, vampires, house ghosts, and occasional "green vomit piles" while picking up the pieces and sorting out what could very well be an eternity in a bizarre, fanciful, and humorous world of ghouls and banned books.
When residents suddenly disappear one by one with no trace and for no logical reason, however, doubts being "housed" in an alternate world for their sins are raised, and time suddenly becomes of the essence as Noah and the rest of Helleville's condemned race to find answers to what's quickly turning into a dangerous puzzle.