Preacher, against his better judgment, agrees to lead a wagon train of women across the West. He hires a pack of mountain men to assist him, but he gets more than he bargained for when a gang of cutthroats follows the train with murder, rape and slave trafficking in mind. Led by the nefarious Easterner Victor Bedell, the outlaws will accomplish what few have done before: they will get a bullet into Preacher. But they'll make a fatal mistake. They'll leave him for dead. Soon the mountains will echo with avenging gunfire.