The American Society of Addiction Medicine Handbook of Addiction Medicine, Second Edition is a practical, evidence-based guide to caring for individuals with substance use disorder. Produced by the largest medical society dedicated to the improvement of addiction care, this new edition adopts non-stigmatizing language related to addiction and includes new material on LGBTQ care, vaping, and harm reduction. The second edition also carefully presents a compassionate, patient-centered approach to care. To learn more about the American Society of Addiction Medicine, and its commitment to providing the best resources for addiction clinicians, please visit http://www.asam.org.