It's been three years since the zombie outbreak almost destroyed the world. Humanity fought back and the Zombie Response Team was created, an organization that has numerous divisions throughout the United States that are dispatched to destroy the dwindling undead population.

Elisabeth Mayfair heads up Team Mayfair. As the Team Leader, she works hard at dispensing and eliminating zombies, and her desire to protect her sister Margo and all she holds dear is her driving force.

But Elisabeth has a secret. She's an Abnormal who gained special abilities after being bit by a zombie. Using her newly acquired skills gives Elisabeth an advantage against the undead. But Abnormals aren't fully understood, and she must keep her condition a secret or risk her own life.

When Elisabeth discovers a zombie uprising in the small town of Pine Valley, Tennessee, she and her team are tested to their limits as they face hordes that appear out of nowhere. As they search for the cause of the new outbreaks, they will uncover a plot that threatens not only the fragile stability of Pine Valley, but the world itself.